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Phase angle and n-3 polyunsaturated fatty acids in sickle cell disease
  1. D J VanderJagt1,
  2. Y-S Huang2,
  3. L-T Chuang2,
  4. C Bonnett1,
  5. R H Glew1
  1. 1Department of Biochemistry and Molecular Biology, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA
  2. 2Ross Products Division, Abbott Laboratories, Columbus, Ohio, USA
  1. Correspondence to:
    Dr R H Glew, Department of Biochemistry and Molecular Biology, Room 249, BMSB, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA;
    rglew{at}salud.unm.edu

Abstract

Phase angle, an impedance parameter used for nutritional assessment, is reflective of the capacitance properties of cell membranes. We have shown a significant correlation between the proportions of specific n-3 polyunsaturated fatty acids in the serum phospholipids of Nigerian children with sickle cell disease and their phase angles determined by bioelectrical impedance analysis.

  • polyunsaturated fatty acid
  • sickle cell disease
  • phase angle
  • BIA, bioelectrical impedance analysis
  • SCD, sickle cell disease

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