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Arch Dis Child 86:453 doi:10.1136/adc.86.6.453
  • Letter

Acrodynia: a case report of two siblings

  1. Y Horowitz,
  2. D Greenberg,
  3. G Ling,
  4. M Lifshitz
  1. Pediatrics Department D, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, PO Box 15, Beer Sheva 8410, Israel; matyl@bgumail.bgu.ac.il
  1. Correspondence to
    Dr Lifshitz

    Acrodynia, a rare disorder, is a form of chronic mercury poisoning.1 We report two siblings who developed the classic clinical picture of acrodynia.

    A 4½12 year old boy was admitted with dysuria, general weakness, and loss of appetite. He had hypertension (140/95 mm Hg) and tachycardia (141 beats/min). He was irritable and depressed, and had a diffuse itching papular rash with palmar erythema and superficial desquamation (fig 1). Initial evaluation revealed a normal complete blood count and a normal blood chemistry. Urine analysis and complement levels were normal. Vanillymandelic acid in a 24 hour urine collection was 22.2 μmol/day. Duplex scan of the renal arteries, …