Editor,—Kerr et al claimH pylori as a potential etiologic factor in SIDS. Fatal systemic ammonia intoxication through hydrolysis of urea by H pylori produced urease in the lungs and trachea, following aspiration of gastric juice, was proposed as a possible pathogenic pathway. In general we cannot agree with this hypothesis. The molecular procedure (nested PCR and ELISA based detection) used in this study could explain some inconsistent data—for example, H pylori DNA detection in lungs or trachea but not in the stomach. Furthermore, it is debatable whether haematoxylin and eosin (H&E) routine staining is an efficient method to …