Article Text
Article
An unusual concurrence of graft versus host disease caused by engraftment of maternal lymphocytes with DiGeorge anomaly
Abstract
We describe a girl with DiGeorge anomaly and normal cytogenetic and molecular studies, whose clinical course was complicated by graft versus host disease caused by intrauterine materno-fetal transfusion, and several immunohaematological alterations including a monoclonal gammapathy of undetermined significance (first IgG, which subsequently changed to IgM). The main clinical features and pathological findings are discussed.
- biclonal gammapathy
- materno-fetal chimerism
- graft versus host disease
- DiGeorge anomaly
- Omenn's syndrome
- Evans' syndrome