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Original article
B cell non-Hodgkin’s lymphoma in a girl with the DiGeorge anomaly
  1. Jose T Ramosa,
  2. Eduardo López-Lasoa,
  3. Jesus Ruiz-Contrerasa,
  4. Elisa Giancasproa,
  5. Santiago Maderob
  1. aDivision of Immunodeficiencies, Department of Pediatrics, Hospital 12 de Octubre, Cra. Andalucia Km 5,400 28041 Madrid, Spain, bDivision of Pathology, Hospital 12 de Octubre
  1. Dr Ramos. Email: jramos{at}h12o.es

Abstract

The DiGeorge anomaly (DGA) is occasionally associated with cellular immunodeficiency. We report a female infant diagnosed with complete DGA, who developed fatal, high grade, non-Hodgkin’s lymphoma that expressed Epstein-Barr virus (EBV). Non-Hodgkin’s lymphoma should be considered in children with DGA.

  • DiGeorge anomaly
  • Epstein-Barr virus
  • B cell lymphoma
  • CATCH 22

https://doi.org/10.1136/adc.81.5.444

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