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Congenital nephrotic syndrome responsive to captopril and indometacin
  1. P A J Heatona,
  2. O Smalesb,
  3. W Wongc
  1. aTaranaki Base Hospital, Private Bag 2016, New Plymouth 4620, New Zealand, bPaediatric Department, Hawkes Bay Hospital, Hastings, New Zealand, cRenal Unit, Starship Children’s Hospital, Auckland 1, New Zealand
  1. Dr Heaton.email: paed.cacc{at}thcl.co.nz

Abstract

Two children with congenital nephrotic syndrome are described (one with Finnish-type nephrosis, the other with diffuse mesangial sclerosis). Both children have had a prolonged and sustained clinical response with good physical health and normal growth patterns using captopril and indometacin as their sole treatment. No adverse effects have been noted. We recommend a trial of indometacin and captopril treatment in cases of congenital nephrotic syndrome.

  • congenital nephrotic syndrome
  • captopril
  • indometacin

https://doi.org/10.1136/adc.81.2.174

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