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Hyperammonaemic encephalopathy after a subureteric injection for vesicoureteric reflux
  1. S M Zuberia,
  2. J B P Stephensona,
  3. A F Azmyb,
  4. P H Robinsonc,
  5. R C McWilliama
  1. aDepartment of Neurology, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK, bDepartment of Surgery, Royal Hospital for Sick Children, cDepartment of Metabolic Medicine, Royal Hospital for Sick Children
  1. Dr Zuberi

Abstract

A 6 year old boy developed hyperammonaemic encephalopathy following a subureteric injection for treatment of vesicoureteric reflux. The hyperammonaemia may be explained by a postoperative urinary tract infection with a urea splitting organism, leading to raised urine ammonia that was absorbed easily across a dilated urinary tract. Agitation and alteration in consciousness level following a urological procedure, in a child with a dilated urinary tract, may be signs of a treatable hyperammonaemic encephalopathy.

  • hyperammonaemia
  • encephalopathy
  • subureteric injection
  • urea splitting organism

https://doi.org/10.1136/adc.79.4.363

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