Arch Dis Child 78:479-480 doi:10.1136/adc.78.5.479
  • Original article

Mononucleosis syndrome and coincidental human herpesvirus-7 and Epstein-Barr virus infection

  1. H-H Chiu,
  2. C-Y Lee,
  3. P-I Lee,
  4. K-H Lin,
  5. L-M Huang
  1. Department of Pediatrics, National Taiwan University Hospital, No 7, Chung-Shan South Road, Taipei, Taiwan, Republic of China
  1. Dr Huang. email: lmhuang{at}
  • Accepted 20 November 1997


Two girls (a 5 year old and a 21 month old) experiencing mononucleosis syndrome with coincidental human herpesvirus (HHV)-7 and Epstein-Barr virus (EBV) infections are described. One patient had primary HHV-7 infection and reactivated EBV infection. The other had primary HHV-7 and EBV infections. These cases indicated that HHV-7 is capable of inducing infectious mononucleosis-like illness. Multiple herpesvirus infection in one of the patients also suggests that interaction among herpesviruses can occur in vivo. The consequence of this interaction may have clinical implications.