Duration of growth suppressive effects of regular inhaled corticosteroids
- aCystic Fibrosis Unit, Department of Child Health, University Hospital of Wales, Heath Park, Cardiff CF4 4XW, bDivision of General Practice, Northern General Hospital, Sheffield, cUniversity Medicine, Southampton General Hospital, Southampton
- Dr Doull.
- Accepted 7 October 1997
The growth of 50 children receiving regular inhaled corticosteroids was segregated into divisions of six weeks from the start of treatment and compared with their growth when not receiving regular corticosteroids using a random effects regression model. Growth suppression was most marked during the initial six weeks after starting treatment, with most suppression occurring during the initial 18 weeks. Thereafter the children’s growth was similar to their growth when not receiving treatment. These findings have important consequences for patterns of treatment of asthma in children.