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Bisphosphonates in osteogenesis imperfecta
  1. N J SHAW
  1. Metabolic Bone Disease Clinic
  2. Department of Endocrinology
  3. Birmingham Children’s Hospital
  4. Ladywood Middleway, Ladywood
  5. Birmingham B16 8ET

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    Editor,—I was interested to read the recent articles by Allgrove1 and Williams et al 2 on the use of bisphosphonates in children and would like to report my experience of their use in a child with osteogenesis imperfecta. The patient was referred to me age 9 years with a history of recurrent fractures since infancy and a family history consistent with osteogenesis imperfecta. She had a nine month history of low back pain, evidence of a thoracolumbar kyphosis, and tenderness over the thoracolumbar spine. She had …

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