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Hypocitraturia in patients with urolithiasis
  1. BERND HOPPE,
  2. CRAIG B LANGMAN
  1. Northwestern University
  2. Children’s Memorial Hospital
  3. Division of Nephrology
  4. 2300 Children’s Plaza # 37
  5. Chicago, Illinois 60614, USA

    https://doi.org/10.1136/adc.76.2.174b

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      Editor,—Akçay et al observed a significantly lower urinary citrate excretion in children with a previous history of urolithiasis.1 Their findings are comparable with data presented in adult stone forming patients, showing a high incidence of hypocitraturia.2 As citrate is a potent inhibitor of calcium-oxalate or calcium-phosphate crystal aggregation,3 hypocitraturia is one important factor influencing recurrent urolithiasis.

      Urinary citrate excretion, expressed as a citrate/creatinine ratio, in idiopathic stone forming children (n = 25) …

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