Arch Dis Child 66:866-869 doi:10.1136/adc.66.7.866
  • Research Article

Children with pervasive refusal.

  1. B Lask,
  2. C Britten,
  3. L Kroll,
  4. J Magagna,
  5. M Tranter
  1. Hospital for Sick Children, London.


      Four children are described with a potentially life threatening condition manifested by profound and pervasive refusal to eat, drink, walk, talk, or care for themselves in any way over a period of several months. The multiplicity and severity of the symptoms in these children do not fit comfortably into any existing diagnostic category. Long term and highly skilled nursing and psychiatric care is required to help these children to recover. The possible causes of this syndrome are discussed.