Article Text


Cellobiose: mannitol differential permeability in small bowel disease.
  1. S Hodges,
  2. S P Ashmore,
  3. H R Patel,
  4. M S Tanner
  1. Department of Child Health, University of Leicester.


    Cellobiose and mannitol absorption were studied in patients with suspected abnormal function of the small bowel mucosa. The urinary cellobiose:mannitol ratio was increased in subtotal villous atrophy, iron deficiency anaemia, and small intestinal Crohn's disease. The test seems a sensitive indicator of the integrity of small bowel mucosa.

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