Airways obstruction was measured before and after inhaled ipratropium bromide in 32 wheezy children aged between 3 months and 2 years 8 months using a total body plethysmograph and a modification of the forced oscillation technique. No relationship was found between age and incidence of response. About 40% of those under age 18 months had an improvement in lung function. This form of treatment may have a place in the management of the wheezy infant too young to respond to beta-2 stimulants.
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