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Comparison of hexachlorophane and chlorhexidine powders in prevention of neonatal infection.
  1. V G Alder,
  2. D Burman,
  3. R A Simpson,
  4. J Fysh,
  5. W A Gillespie

    Abstract

    The protective effect of treating the skin of newborn infants with powders containing 1% chlorhexidine or 0.33% hexachlorophane was compared. Each was equally effective in preventing colonisation and infection by Staphylococcus aureus. In contrast, the skin became profusely colonised by coagulase-negative staphylococci, irrespective of the powder used. Venous blood concentrations of chlorhexidine were low or undetectable in the few infants whose blood was analysed.

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