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Asphyxiating thoracic dysplasia. Clinical, radiological, and pathological information on 10 patients.
  1. F Oberklaid,
  2. D M Danks,
  3. V Mayne,
  4. P Campbell

    Abstract

    Review of 10 cases of asphyxiating thoracic dysplasia has shown a wide range of clinical effects and some variability in the radiographic features. Respiratory difficulty was severe in 7 babies and lethal in 6 of these. The seventh child is remarkable for his normal stature and excellent health at 15 years of age. 3 babies had no respiratory difficulty but 2 of them subsequently died of renal failure; one remains alive at 3 years. Microscopical abnormalities in the liver and kidneys were very frequent and appeared to increase progressively with age.

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