Article Text

PDF

Relation between changes in plasma calcium in first week of life and renal function.
  1. L Stimmler,
  2. G J Snodgrass,
  3. Y Gupta,
  4. J K Stothers,
  5. D Brown

    Abstract

    (1) Of 71 infants fed on reconstituted dried or evaporated cow's milk, 31 showed a fall in plasma calcium between the 1st and 6th days of life, whereas in 35 breast-fed infants this occurred in only 5. (2) Those artificially-fed infants who had shown a rise in plasma calcium over this period had significantly lower plasma creatinine values and significantly higher excretion of creatinine than those infants who showed a fall in calcium levels. (3) Artificially-fed infants who had shown a rise in calcium had significantly lower plasma osmolality and significantly higher osmolar excretion in the urine than those infants who showed a fall in plasma calcium. (4) It is suggested that a delay in the normal increase in glomerular filtration rate during the first week of life in some infants leads to phosphate retention. This, together with a higher dietary intake of phosphate, leads to a decrease of the plasma calcium to hypocalcaemic levels.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.