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Rates of creatinine clearance in babies less than one week of age
  1. Hüseyin Sertel,
  2. Jon Scopes

    Abstract

    Rates of creatinine clearance were measured in normal newborn babies by collecting a timed specimen of voided urine and estimating plasma creatinine. Each of the 17 babies had the estimation on day 1 and on day 6 of life. The mean rate on day 1 was 17·8 ml/minute per 1·73 m2, and there was a significant and systematic increase by day 6 when the mean rate was 36·4 ml/minute per 1·73 m2. The findings are important when assessing fluid requirements and drug dosage in the newborn.

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