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Comparative trial of 2 weeks and 8 weeks cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood
  1. T. M. Barratt,
  2. J. S. Cameron,
  3. C. Chantler,
  4. C. S. Ogg,
  5. J. F. Soothill

    Abstract

    A comparative trial of 2 weeks and 8 weeks cyclophosphamide therapy given during steroid-maintained remission in 32 children with steroid-sensitive relapsing nephrotic syndrome of childhood is reported. A significantly greater number of the 16 children who received 2 weeks therapy relapsed after steroid withdrawal than of those who received 8 weeks therapy. Relapses occurred later after 2 weeks cyclophosphamide therapy than in our previous experience of steroid treatment alone.

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