Article Text

PDF

Quantitative growth and development of human brain
  1. John Dobbing,
  2. Jean Sands

    Abstract

    One hundred and thirty-nine complete human brains ranging in age from 10 weeks' gestation to 7 postnatal years, together with 9 adult brains, have been analysed in order to describe the human brain growth spurt quantitatively. The three major regions were examined for weight, DNA, cholesterol, and water content. The growth spurt period is much more postnatal than has formerly been supposed. The cerebellum has special growth characteristics; and there is a separate period from 10 to 18 weeks' gestation when adult neuronal cell number may largely be achieved. The implications of these findings for the vulnerability of developing brain are discussed.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.