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Growth of Children with Thalassaemia
  1. C. Kattamis,
  2. N. Touliatos,
  3. S. Haidas,
  4. N. Matsaniotis

    Effect of Different Transfusion Regimens

    Abstract

    Growth was studied in 74 children with homozygous β-thalassaemia aged 1 to 11 years, treated with three different transfusion regimens.

    In group I (38 cases) haemoglobin levels were maintained above 8 g./100 ml.; in group II (14 cases), pretransfusion haemoglobin levels ranged between 6 and 8 g./100 ml.; in group III (22 children), pretransfusion haemoglobin levels were below 6 g./100 ml.

    Children in group I grew normally, both in weight and height; those in groups II and III were retarded, particularly those in group III.

    Frequent transfusions, in spite of their disadvantages, at present constitute the treatment of choice.

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    Effect of Different Transfusion Regimens