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Differential Protein Clearances in Indian Children with the Nephrotic Syndrome
  1. R. K. Chandra,
  2. S. S. Manchanda,
  3. R. N. Srivastava,
  4. J. F. Soothill

    Abstract

    Differential clearances of five plasma proteins were studied in 37 north Indian children with the nephrotic syndrome, and these, and the serum β1c levels were related to steroid response and, in some, renal biopsy histology. 16 children (43%) did not respond completely to steroids and a majority of them had a poorly selective proteinuria. The differential protein clearances suggest that these patients are a heterogeneous group. The serum complement β1c levels in nephrotics were significantly lower than in control Indian and European children.

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