Article Text


Treatment of Children with Acute Amoebic Dysentery
  1. C. J. Rubidge,
  2. J. N. Scragg,
  3. S. J. Powell


    Metronidazole cured 17 out of 20 children with acute amoebic dysentery. The 3 failures were later treated with dehydroemetine, tetracycline, and diloxanide furoate, but 2 required further courses of amoebicides before they were cured. A combination of dehydroemetine, tetracycline, and diloxanide furoate produced cure in 16 out of 19 children. The 3 failures were subsequently treated with metronidazole. 2 were cured; the remaining patient did not reattend for follow-up.

    Metronidazole is as effective as the previously favoured combined regimen of amoebicides in children with amoebic dysentry. It is a safe and simple form of treatment.

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    Comparative Trial of Metronidazole against a Combination of Dehydroemetine, Tetracycline, and Diloxanide Furoate

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