Background It was marked that children with increased BMI have high height due to insulin resistance or elevating insulin/IGF1. The Insulin resistant can be reason of cardio-vascular diseases.
Aim to find the early detection of risk factors for cardiovascular diseases in children with height≥85 percentile age-sex norm
Methods 854 children aged 3–17 y.o. were examined (included 87 with height≥85 percentile): by arterial stiffness device (TensioMed,Hungary) – 211; by 24 hour monitoring of ECG and blood pressure(Astrocard, Russia) – 92; by Polysomnography (Embla-S7000,USA)- 45; by system of continuous glucose monitoring (Guardian, USA) – 14 children.
Results Children with increased BMI and with height≥85 percentile in comparison with middle height had a significantly lower augmentation index, in 5 times more often – decreased diastolic blood pressure at night, lower level of high density lipoproteids; if they had obesity- the normal 24 hour dynamics of blood pressure was disappeared, if they had overweight- there was more longer QT interval at night, if they had sleep obstructive apnea-hypopnea syndrom there were some periods of glycemia less then 3.3 mmol/L at night.
Conclusions Children with height≥85 percentile of age- and gender-based norms with increased BMI and, especially, with nasal obstruction have an additional risk of cardio-vascular diseases.
Disclosure of Interest None Declared
- cardiovascular risk factors
- blood pressure
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