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P62 Situs inversus viscerum and renal agenesis in a newborn
  1. Nardella G1,
  2. Candela MA2,
  3. Verrotti di Pianella V1,
  4. Lanzano A1,
  5. Soldano L1,
  6. Gorgoglione S1,
  7. Calabrese C1,
  8. Di Gianni AM2,
  9. Lozupone S2,
  10. Maffei G2,
  11. Popolo G2,
  12. Villani G2,
  13. Pettoello-Mantovani M1,
  14. Magaldi R1
  1. 1Department of Paediatrics, Hospital-University, Foggia, Italy
  2. 2Department of Neonatology and Neonatal Intensive Care Unit, Hospital-University, Foggia, Italy


Situs inversus viscerum is a rare congenital anomaly (incidence 1/15–20 000) in which organs are mirrored from their normal positions. It is called situs inversus viscerum totalis when there is a total transposition of abdominal and thoracic viscera. Incomplete situs inversus viscerum involves transposition only of abdominal organs and is more frequently associated with congenital cardiac defects (90%–95% vs 5%–10% in situs inversus totalis). About 25% of individuals with situs inversus have an underlying condition known as Kartagener Syndrome. As a result of benign pathology, patients with situs inversus viscerum can live normal healthy lives. Situs viscerum inversus can be associated with defects in various organ systems (respiratory, GI tract, genitourinary). In literature there’s evidence of cases of situs inversus associated with renal malformations (dysplasia, hypoplasia, ectopia, polycystic kidney, horseshoe kidney). Association with renal agenesis is rare. We report the case of S., born at 40 weeks, eutocic delivery. APGAR 8/9, weight 3350 g. Normal fetal US. In the third day of life, heart sounds better heard on the right side of the chest. Cardiac US: situs inversus viscerum, dextrocardia, subaortic stenosis, restrictive ventricular septal defect, atrial septal defect ostium secundum. In the fourth day of life, abdominal US findings were suggestive of right renal agenesis. In the 20th day of life, right reducible inguinal hernia. The little patient underwent cystography, negative for vesicoureteral reflux, and static renal scintigraphy with evidence of absent activity in right renal space. Renal function, cerebral US, audiologial assessment and karyotype were normal. No respiratory distress reported. Mucociliary clearance test and a regular follow-up are scheduled.

  • situs inversus viscerum
  • dextrocardia
  • renal agenesis

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