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G100 Correlation between maternal and childhood VIT B12, folic acid and ferritin levels
  1. FZ Zeeshan1,
  2. AB Bari2,
  3. SF Farhan1,
  4. UJ Jabeen1,
  5. AWR Rathore1
  1. 1Paediatric Medicine, Children Hospital, Lahore, Pakistan
  2. 2Microbiology, Children Hospital, Lahore, Pakistan

Abstract

Objective To determine the biochemical parameters of anaemia between mother and child and to study risk factors as a cause of anaemia.

Methodology A total of 180 children 2 months to 2 years of age admitted from January 2014 to January 2015 having anaemia were included. Complete blood count (CBC), serum ferritin level, folic acid and vit B 12 level were sent of children and their mothers. Data was analysed using SPSS version 20.

Results Total 180 children with anaemia were enrolled into the study.Out of these 120 (66.7%) were males and 60 (33.3%) were females with M:F ratio was 2:1. The mean age of children was 7.3±5.6 months.The distribution of anaemia according to severity. 55% were malnourished Prematrure children had lower folic acid levels (p=0.02)while prematurity and IUGR, previous admission and h/o sepsis showed no association with anaemia in our study. Fifty three percent children had complete vaccination. Both breast-feeding and top feeding showed significant association with anaemia with p-value of 0.042 and 0.003 respectively while dilution showed no impact on anaemia.

The mean Hb of children was 8 g/dl. In our data only 7 children had ferritin less than 4 ng/ml (4%)while 60% had low folic acid levels and 45% had decreased vitB12 levels.

Mean maternal age was 26.5±5.5 years.. Mean maternal Hb was10.4±1.45 g/dl.The relationship between Hb of mother and child was significantly associated (p=0.02).The children with low ferritin values also belonged to iron deficient mothers(p <0.001). Mothers who had vit B12 deficiency also had children with low vit B12 levels (p=0.008)while there was no significant correlation observed between maternal and child folic acid levels(p=0.8)

Conclusion Maternal anaemia has a significant impact on child’s haemoglobin and nutritional status.As compared with previous concept of increased iron deficiency in children,we found of increased occurrence of folic acid and vitB12 deficiency in children.

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