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Procalcitonin and febrile infants

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If asked what would be top of their wish-list, my guess is that most acute paediatricians would want a test to be used in febrile infants that could exclude serious bacterial infection reliably, quickly and simply. We know that the majority will turn out to have a viral cause but identifying the few with bacterial infections is difficult, resulting in hospital admissions and much investigation and treatment that turns out to be unnecessary. Infants under 3 months are the most difficult, as clinical signs can be non-specific and lab tests …

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