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G143(P) Cerebral function monitoring (cfm) as a prognostic bedside tool
  1. J Murali,
  2. S Dutta,
  3. NB Soni
  1. Neonatal Intensive-Care Unit, East Lancashire Hospitals Trust, Burnley, UK

Abstract

Background and aims CFM is routinely used for monitoring babies undergoing Therapeutic Hypothermia. There is limited evidence linking the relationship of the change in the CFM trace during cooling to Mortality or HIE changes on MRI. We aim to assess any such link.

Results Study period 5 years (Sept 09–Aug14). Total number 76

CFM and MRI CFM trace was persistently severely abnormal at the end of the cooling period in (19/76 =25%). In this group 47% died, 47% had HIE changes on MRI and one baby (6%) had normal MRI. However in babies where CFM normalised at end of cooling (35/76 = 46%), there was no mortality. MRI scans were normal in 43% and 37% had HIE changes on MRI.

MRI In mortality group (n = 15), 11 babies died before undertaking MRI. HIE changes were found in 4 babies (100%) who had MRI. In the survivor group, MRI was performed in 98%. Scans showed HIE changes in 50% and 35% were normal.

Conclusion Analysis that persisting severely abnormal CFM tracing at the end of cooling is indicative of high probability of mortality and/or HIE changes on MRI. Although normalisation of CFM pattern is not associated with any mortality from our data, it does not preclude the HIE changes on MRI. We believe that CFM is a helpful bedside diagnostic tool for assessing extent of hypoxix brain injury and it helps in counselling parents

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