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G63(P) Disease pattern, bacteriological profile and outcome of childhood acute bacterial meningitis
  1. A Bari,
  2. F Zeeshan,
  3. A Mushatq,
  4. M Nazar
  1. Pediatric Medicine, Children’s Hospital, Lahore, Pakistan

Abstract

Aim To determine the disease pattern, etiological agents and outcome of childhood acute bacterial meningitis

Study design Descriptive observational study.

Place and duration of study

The Children’s Hospital and Institute of Child Health, Lahore, from Jan, 2012 to Dec, 2012.

Statistical analysis SPSS 16.0 version

Results Out of 199 pateints 36% were female and 64% male.

68.4% were between 2 months and 1 year

26.6% were between 1.1 and 3 years

10% were between 3.1 and 5 years

97% presented with fever

87% with poor feeding

25% with fits

10% with crying

23% with altered conscious level

13% with signs of mniengeal irritation

Vaccination was incomplete in 7% unvaccinated 45% and vaccinated 48%.

Complications 1% had hydrcephalus, 0.5% had subdural effusions, 4.5% had motor loss 10% have seizures maximum no of deaths less than 1 year. Malnutrition was associated with deaths in 31% and csf culture positivity in 25% (Figures 1, 2, 3).

Abstract G63(P) Figure 2

Microbiological diagnosis based on CSF cultures according to age

Abstract G63(P) Figure 3

Deaths in correlation with age, severe malnutrition and CSF culture positivity n = 20

Conclusion Maxium no of deaths in males under 1 year, 33% with malnutritiion, 25% with csf culture positivitity coagulase negative staph aureus and streptoccoccus pneumnia were two most commoon pathogens in culture.

Mortality under one year was maximun and associated with streptococcus pneumonia.

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