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Abstract
Aim To determine the disease pattern, etiological agents and outcome of childhood acute bacterial meningitis
Study design Descriptive observational study.
Place and duration of study
The Children’s Hospital and Institute of Child Health, Lahore, from Jan, 2012 to Dec, 2012.
Statistical analysis SPSS 16.0 version
Results Out of 199 pateints 36% were female and 64% male.
68.4% were between 2 months and 1 year
26.6% were between 1.1 and 3 years
10% were between 3.1 and 5 years
97% presented with fever
87% with poor feeding
25% with fits
10% with crying
23% with altered conscious level
13% with signs of mniengeal irritation
Vaccination was incomplete in 7% unvaccinated 45% and vaccinated 48%.
Complications 1% had hydrcephalus, 0.5% had subdural effusions, 4.5% had motor loss 10% have seizures maximum no of deaths less than 1 year. Malnutrition was associated with deaths in 31% and csf culture positivity in 25% (Figures 1, 2, 3).
Microbiological diagnosis based on CSF cultures according to age
Deaths in correlation with age, severe malnutrition and CSF culture positivity n = 20
Conclusion Maxium no of deaths in males under 1 year, 33% with malnutritiion, 25% with csf culture positivitity coagulase negative staph aureus and streptoccoccus pneumnia were two most commoon pathogens in culture.
Mortality under one year was maximun and associated with streptococcus pneumonia.