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Outcomes in children with protracted bacterial bronchitis confirmed by bronchoscopy
  1. Mark G Pritchard1,
  2. Warren Lenney1,2,
  3. Francis J Gilchrist1,2
  1. 1Academic Department of Child Health, University Hospital of North Staffordshire, Stoke-on-Trent, UK
  2. 2Institute for Science and Technology in Medicine, Keele University, Guy Hilton Research Centre, Stoke-on-Trent, UK
  1. Correspondence to Dr Francis J Gilchrist, Academic Department of Child Health, University Hospital of North Staffordshire, Newcastle Road, Stoke-on-Trent ST4 6QG, UK; francis.gilchrist{at}uhns.nhs.uk

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Protracted bacterial bronchitis (PBB) is increasingly recognised as a cause of chronic cough in children.1 It is characterised by bacterial infection of the conducting airways that produces an antibiotic responsive wet cough.2 At our centre, children with suspected PBB are treated empirically with a 2-week course of amoxicillin/clavulanic acid. If they do not respond or their symptoms relapse, then flexible bronchoscopy with bronchoalveolar lavage (FB-BAL) is undertaken to obtain a microbiological diagnosis. In those whom PBB is confirmed, a prolonged course of an appropriate antibiotic is prescribed. There are relatively little data available on response to treatment, but it was our experience a high percentage of children were experiencing relapses of their wet cough after initial treatment. We therefore undertook a retrospective review …

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