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The most recent version of this article was published on 1 May 2008

Arch Dis Child. Published Online First: 1 October 2007. doi:10.1136/adc.2007.131342
Copyright © 2007 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.

Archimedes

Is the frequency of recurrent chest infections, in children with chronic neurological problems, reduced by prophylactic Azithromycin?

Charlotte B Kirk 1*

1 Royal Hospital for Sick Children, Edinburgh, United Kingdom

* To whom correspondence should be addressed. E-mail: charlotte{at}kirkfamily.co.uk.

Accepted 25 September 2007


Abstract

Prophylactic Azithromycin may decrease the frequency of respiratory exacerbations in children with severe neurological impairment and chronic lung disease (grade B) Prophylactic Azithromycin should not produce serious or life-threatening side effects in this population (grade B)

Keywords: Azithromycin, Chest Infection, Chronic Neurological Impairment, Macrolide antibiotic


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Antibiotic Prophylaxis for Aspiration: The Limits of Extrapolation
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