Arch Dis Child. Published Online First: 1 October 2007. doi:10.1136/adc.2007.131334
Archimedes |
Should gonadotropin releasing hormone analogue be administered to prevent premature ovarian failure in young women with systemic lupus erythematosus on cyclophosphamide therapy?
1 British Columbia's Children's Hospital, Canada
* To whom correspondence should be addressed. E-mail: rajivsinha_in{at}yahoo.com.
Accepted 25 September 2007
Abstract
1) Young women suffering from SLE treated with CYC have a high risk of ovarian failure. [Grade C]
2) GnRH is a promising option for ovarian preservation in SLE but should currently be regarded as an experimental therapy.
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