Arch Dis Child. Published Online First: 3 September 2007. doi:10.1136/adc.2006.114249
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Monitoring of concordance in growth hormone therapy
1 Addenbrooke's Hospital, United Kingdom
2 University of Cambridge, United Kingdom
* To whom correspondence should be addressed. E-mail: cla22{at}cam.ac.uk.
Accepted 31 July 2007
Abstract
Concordance with growth hormone therapy in 75 children was objectively assessed through data on GP prescriptions over 12-months. 23% missed >2 injections/week. Lower concordance was associated with: longer duration on GH therapy (p<0.005), lack of choice of delivery device (p<0.005), and short prescription durations (p<0.005), and predicted lower height velocities (p<0.05).
Keywords: concordance, growth hormone therapy, objective monitoring
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