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The most recent version of this article was published on 1 May 2006

Arch Dis Child. Published Online First: 31 January 2006. doi:10.1136/adc.2005.085191
Copyright © 2006 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.

Original articles

Patterns of disease in Sri Lankan Paediatric dengue patients

Neelika Malavige 1, P K Ranatunga 2, V N Velathanthiri 1, Sirimali Fernando 1, D H Karunatilaka 3, John Aaskov 4 and Suranjith Luke Seneviratne 5*

1 University of Jayawardenapura, Sri Lanka
2 Lady Ridgeway Hospital for Children, Sri Lanka
3 Lady Ridgeway Hospital, Sri Lanka
4 Arbovirus Reference Centre, Australia
5 John Radcliffe Hospital, Oxford, United Kingdom

* To whom correspondence should be addressed. E-mail: suran200{at}yahoo.co.uk.

Accepted 18 January 2006


Abstract

Dengue is the most important mosquito borne viral infection in the world, with nearly 90% of infections occurring in children. However, at present, detailed published clinical and laboratory information relating to children with dengue infections living in South Asia is generally lacking. Epidemics of dengue occur regularly in Sri Lanka, with the largest and most severe epidemic occurring in 2004. We describe the patterns of clinical disease in a cohort of Sri Lankan children hospitalized with dengue during this major epidemic and highlight differences in clinical and laboratory findings in this group from those reported previously. Oral candidiasis was seen in 18% of these children. To the best of our knowledge this clinical manifestation has not been previously documented in children suffering with acute dengue in Sri Lanka or elsewhere.

Keywords: Candia, Sri Lanka, clinical findings, dengue, laboratory findings


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