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Published Online First: 9 January 2007. doi:10.1136/adc.2006.093823
Archives of Disease in Childhood 2008;93:285-287
Copyright © 2008 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health
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Original articles

Hyponatraemia and hypokalaemia during intravenous fluid administration

K Armon1, A Riordan2, S Playfor3, G Millman4, A Khader5, for the Paediatric Research Society

1 Norfolk and Norwich University Hospital NHS Trust, Norwich, Norfolk, UK
2 Paediatric Infectious Diseases and Immunology, Royal Liverpool Children’s Hospital (Alder Hey), Liverpool, UK
3 Paediatric Intensive Care Medicine, Royal Manchester Children’s Hospital, Manchester, UK
4 Pediatrics, York Hospital, York, UK
5 Paediatrics, Addenbrooke’s Hospital, Cambridge, UK

Correspondence to:
Kate Armon, Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, Norfolk NR4 7UY, UK; kate.armon{at}nnuh.nhs.uk

Background: Hospital-acquired hyponatraemia is associated with excessive volumes of hypotonic intravenous fluids and can cause death or permanent neurological deficit.

Methods: A cross-sectional survey was carried out in 17 hospitals on all children receiving intravenous fluids during 1 day of a specified week in December 2004.

Results: 77 of 99 children receiving intravenous fluids received hypotonic solutions and 38% received >105% of fluid requirements. 21 of 86 children were hyponatraemic, but the electrolytes of only 79% had been checked in the preceding 48 h.

Conclusions: Intravenous fluids should be used with caution as regards the tonicity and volume administered, and with appropriate monitoring of serum electrolytes.




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Hyponatraemia and hypokalaemia due to intravenous hypotonic solutions in the children
Ahmet Sert, et al.
ADC Online, 26 Aug 2008 [Full text]

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