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Archives of Disease in Childhood 2007;92:474-475; doi:10.1136/adc.2006.115295
Copyright © 2007 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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PERSPECTIVE

Hypernatraemic dehydration

Avoiding hypernatraemic dehydration in healthy term infants

Neena Modi

Correspondence to:
Correspondence to:
Neena Modi
Imperial College London, Chelsea and Westminster Campus, 369 Fulham Road, London, UK;n.modi@imperial.ac.uk


Perspective on the paper by van Dommelen et al (see page490)

The first 150 words of the full text of this article appear below.

Hypernatraemic dehydration arises when there is a disproportionate deficit of body water relative to body sodium. Although the serum sodium concentration is elevated, whole body sodium content may be reduced, unchanged or increased. When the condition occurs in an otherwise healthy full term, breast-fed baby the cause is poor milk intake. In this situation there is loss of body sodium but a greater deficit in body water.

Hypernatraemic dehydration may have serious adverse consequences. At the most severe end of the spectrum these include cerebral oedema, convulsions, venous sinus thrombosis, intracranial haemorrhage, disseminated intravascular coagulation, renal failure, permanent brain injury and death. Infants admitted to hospital usually undergo extensive investigation and rehydration with intravenous fluids and formula. This has led to concern about how best to detect the condition, particularly in newborns in the community as biochemical testing would require referral to hospital. In this issue, a group . . . [Full text of this article]


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This article has been cited by other articles:


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J. Fawke, W P Whitehouse, and V. Kudumula
Monitoring of newborn weight, breast feeding and severe neurological sequelae secondary to dehydration
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Ignorance is bliss ?
SIMON BIRCH
ADC Online, 22 Jun 2007 [Full text]



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