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Archives of Disease in Childhood 2009;94:556-559; doi:10.1136/adc.2008.153635
Copyright © 2009 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.

ARCHIMEDES

QUESTION 2

P Anoop, M A Anjay

St George’s Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK; docanoop@yahoo.com
James Paget University Hospitals NHS Foundation Trust, Gorleston, Great Yarmouth, UK

The first 150 words of the full text of this article appear below.


ROLE OF ANTIBIOTIC LINE LOCKS IN THE TREATMENT OF INFECTED CENTRAL VENOUS ACCESS DEVICES

You are the specialist registrar in paediatrics in a district general hospital which provides shared care for paediatric oncology patients. A girl on cyclical maintenance chemotherapy for acute lymphoblastic leukaemia was admitted 10 days ago with neutropenic sepsis. Blood culture from her Hickman line at admission had grown Staphylococcus epidermidis. She was treated according to the sensitivity pattern of the organism. She is now free of signs of systemic infection. However, the most recent blood culture from her Hickman line continues to grow S epidermidis. Concurrent peripheral venous blood cultures are sterile.

At this point, you are keen to remove the central line. However, her parents want to avoid line removal as venous access has always been extremely difficult for her. You consult the oncologist at her referral centre, who suggests a trial of antibiotic lock of the Hickman line. The microbiologist at your hospital is not in . . . [Full text of this article]


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