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Correspondence to:
Edited by Bob Phillips
| The first 150 words of the full text of this article appear below. |
Archimedes seeks to assist practising clinicians by providing "evidence-based" answers to common questions that are not at the forefront of research but are at the core of practice (format adapted from BestBETs published in the Emergency Medicine Journal). A full description of the format is available online at http://adc.bmj.com/ifora/archimedes.dtl.
Readers wishing to submit their own questions—with best evidence answers—are encouraged to review those already proposed at www.bestbets.org. If your question still hasn’t been answered, feel free to submit your summary according to the instructions for authors at http://adc.bmj.com/ifora/archimedes.dtl.
In examining a diagnostic test, we make the assumption that the characteristics of the test – its sensitivity and specificity (or likelihood ratios (LRs), the way I prefer to think) – will stay constant across different populations, although the positive and negative predictive values will change. This is sort of true, and sort of false.
(Just a reminder:
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