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Maternal vitamin D status and breast milk concentrations of calcium and phosphorus

¹ Department of Paediatric Medicine, Saint Mary’s Hospital for Women & Children, Manchester, UK
² MRC Human Nutrition Research, Cambridge, UK
³ Trafford Primary Care Trust, Manchester, UK
⁴ Central Primary Care Trust, Manchester, UK
⁵ Department of Medicine, University of Manchester, Manchester, UK

Correspondence to:
Dr Zulf Mughal, Department of Paediatric Medicine, Saint Mary’s Hospital for Women & Children, Hathersage Road, Manchester M13 0JH, UK; zulf.mughal@cmmc.nhs.uk

The first 150 words of the full text of this article appear below.

Causes of rickets include vitamin D deficiency, inherited disorders of vitamin D metabolism, dietary calcium deficiency and disorders of renal re-absorption of phosphorus.¹ We have recently seen cases of rickets in exclusively breastfed infants <6 months old born to vitamin D deficient mothers. This observation led us to speculate that rickets in such infants might arise in part because of low breast milk concentrations of calcium and phosphorus. Therefore, the aim of this pilot study was to compare calcium and phosphorus concentrations in the breast milk of vitamin D deficient and replete mothers.

A total of 14 veiled women of Arab origin, known to be at high risk of vitamin D deficiency,² and 10 white Caucasian women took part in the study, which was approved by the North Manchester Research Ethics Committee. All the subjects were between 9 and 13 weeks post-partum and were exclusively breast feeding their infants. . . . [Full text of this article]