Letters by Burn, Stone and Wakefield: author’s response
Accepted 1 July 2008
| The first 150 words of the full text of this article appear below. |
In our paper1 we specifically explored the hypothesis linking autism spectrum disorder (ASD) to MMR vaccination. Our cohort is approximately 9 years from their MMR vaccination but our findings are identical to those of D’Souza et al2 whose subjects were 26–30 months from vaccination. Singh’s paper on measles antibody levels in autism compared with controls reports on a wide age range of children.3
Two correspondents refer to 735 "lost" children. This is a misunderstanding. As described in Baird et al,4 the original study design intended that only a subsample of those screened would be assessed in depth and these were selected at random within strata formed by Social Communication Questionnaire (SCQ) screen score and local ASD diagnosis.
It would certainly have been better if all the children with special educational needs (SEN) and ASD had been able to give satisfactory blood samples, but this was a study with informed
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Arch. Dis. Child. 2008 93: i.[Extract] [Full Text] [PDF]
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