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Gastroenterology, hepatology and nutrition

G/TUES/GAS1 THE SIGNIFICANCE OF COMMON BILE DUCT DILATATION IN NEONATES PRESENTING WITH CHOLESTASIS
E. Fitzpatrick, P. Farrant, J. Karani, M. Davenport, G. Mieli-Vergani, A. Baker.King’s College Hospital, London, UK

Introduction: The ultrasound finding of common bile duct (CB) dilatation (CBD) in jaundiced infants is often of uncertain significance. We wished to clarify the diagnostic and prognostic significance of CBD in infants 3 months old presenting to a National Paediatric Liver Centre over a five-year period.

Methods: We reviewed the clinical, radiological and laboratory data of all infants <3 m with CBD >1.2 mm to determine mode of presentation, diagnosis, interventions and long-term outcome. Data were analysed with Epi-Info.

Results: Seventy eight infants (42 male) were identified, all of whom were initially referred with conjugated hyperbilirubinaemia. The mean gestation was 36.8 (SD 4.6) weeks. At presentation the mean CB size was 2.96 (SD 2.24) mm. Inspissated bile syndrome was shown in 49 (62.8%), 8 (10.3%) had causes of haemolysis. Choledochal cyst was found . . . [Full text of this article]