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Archives of Disease in Childhood 2007;92:646-647; doi:10.1136/adc.2007.117002
Copyright © 2007 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health
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Safety of anti-infective agents for skin preparation in premature infants

Report by Edited by S Upadhyayula1, M Kambalapalli2, C J Harrison2

Edited by Bob Phillips

Rotherham General Hospital, Rotherham, UK; doctorshankar2000@hotmail.com
Rotherham General Hospital, Rotherham, UK

The first 150 words of the full text of this article appear below.

A baby sustained extensive skin burns after the use of a skin preparation (alcoholic chlorhexidine). Following this event the hospital started using an aqueous preparation of chlorhexidine 0.05%. Was this the right choice and what is the evidence for the use of this or any other skin preparation in preterm infants?


Structured clinical question
In preterm infants of <28 weeks’ gestation [patient] what is the choice of skin preparation prior to invasive procedures on the unit [intervention] in terms of safety or least complications and prevention of infection [outcome]?


Search strategy and outcome
Primary source: Medline (1956–2005), MeSH terms were used. An advance search was carried out and close matches from mapping were chosen and another search was carried out using explode and major subheadings. Secondary sources: Cochrane and EMBASE.

Search terms: Premature and anti-infective agents and invasive procedures and safety and complications.

Search outcome: Only four hits matched all our search criteria. . . . [Full text of this article]




eLetters:

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No arachis oil in octenidine preparations
Joerg Siebert
ADC Online, 24 Aug 2007 [Full text]

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