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ARCHIMEDES |
Edited by Bob Phillips
Royal Liverpool Childrens Hospital, UK; liza.mccann@rlc.nhs.uk
| The first 150 words of the full text of this article appear below. |
A 12-year-old girl with rheumatoid factor negative polyarticular juvenile idiopathic arthritis (JIA) attends an outpatient appointment with her mother. Her disease has been controlled by subcutaneous methotrexate, but over the past month, she has stopped taking medication because of adverse effectsin particular, nausea and vomiting after administration of methotrexate injection. On examination, she is found to have a flare of her disease with 10 swollen inflamed joints and early morning stiffness for 2 h/day. You apply for funding for anti-tumour necrosis factor (TNF) treatment and, in the meantime, plan to treat her disease flare with a course of prednisolone. On discussion during the consultation, her mother tells you that she has had a letter from the general practitioner asking her child to attend for a flu vaccination and asks your advice.
Structured clinical questions
Do children with JIA [patient] who become infected with influenza [intervention] have
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