LEADING ARTICLE
Low-risk febrile neutropenia
Treating low-risk febrile neutropenia: Jennys story
1 Department of Paediatric Oncology, St Jamess Hospital, Leeds, UK
2 Department of Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, UK
3 Department of Haematology/Oncology, Great Ormond Street Hospital, London, UK
Correspondence to:
Correspondence to:
Dr J C Chisholm
Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK;chishj@gosh.nhs.uk
Accepted 7 August 2006
Some paediatric patients with cancer can be treated with antibiotic regimens of reduced intensity and duration
| The first 150 words of the full text of this article appear below. |
Jenny is an imaginary 4-year-old girl on maintenance treatment for acute lymphoblastic leukaemia. She gets a cold and a temperature of 38.3°C, and her parents take her to the local hospital. Examination shows no apparent cause of infection, but her temperature remains increased and her neutrophil count is low at 0.7x109/l. Today, in the UK, the manner in which local hospitals treat such an episode varies considerably. After appropriate investigation, including blood and urine cultures, Jenny may be sent home with a recommendation to return if she becomes unwell, or if her temperature continues over the next few days, she may be started on oral antibiotics as an inpatient, with discharge after 48 h, or she may be started on intravenous antibiotics with a view to discharge on oral antibiotics at 48 h, or she may stay in hospital on intravenous antibiotics for a
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