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Rheumatology and radiology joint session

G118 REVIEW OF POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME
D. Peake, S. Carter, S. Philip, L. MacPherson, E. Wassmer.Birmingham Children’s Hospital, Birmingham, UK

Introduction: Posterior reversible encephalopathy syndrome (PRES) is a recently recognised neurological syndrome¹ that mainly affects the cerebral white matter and characteristically shows diffuse hyperintensity predominantly involving the parieto-occipital white matter on T2 weighted MRI. It has a rapidly evolving clinical course.

Aim: To review retrospectively presentation, aetiology, intervention, and outcome of all cases of PRES admitted to Birmingham Children’s Hospital from 1997–2005.

Method: Children with a diagnosis of PRES were ascertained retrospectively from the hospital radiology and paediatric neurology databases. Clinical notes and neuroimaging were reviewed.

Results: Seven children (3 male:4 female) aged 0.5 to 13 years (mean 6.5 years) had a clinical and radiological diagnosis consistent with PRES. Two patients had acute lymhoblastic leukaemia, two were post liver transplantation, and three patients had underlying renal disease. The aetiology in four cases was associated with . . . [Full text of this article]