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Intensive care

G83 PROCALCITONIN VERSUS C-REACTIVE PROTEIN AND IMMATURE-TO-TOTAL NEUTROPHIL RATIO AS MARKERS OF INFECTION AFTER CARDIOPULMONARY BYPASS IN CHILDREN
D. Y. Park, P. McMaster.University Hospital of North Staffordshire, Stoke-on-Trent, UK

Objective: This report is composed of two studies. In the first study, plasma concentrations of procalcitonin (PCT), C-reactive protein (CRP) and of immature-to-total neutrophil ratio (ITR) were measured after cardiac surgery to analyse postoperative induction of PCT. The aim of second study is then to test the hypothesis that PCT is a more reliable marker of infection than CRP or ITR in the post cardiopulmonary bypass (CPB) child.

Methods: PCT, ITR, and CRP were measured serially in 283 post CPB children on the first, second, third, and fifth postoperative day. When a post CPB patient is suspected or proven to have an infection, the researchers in PICU will approach the family for written consent to retrieve any remaining blood and serum from haematology and biochemistry (the laboratories retain any unused specimen for seven days following collection). Overall 65 . . . [Full text of this article]