HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in ADC Online Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content

Dermatology

G55 GASTROINTESTINAL PROBLEMS IN EPIDERMOLYSIS BULLOSA
E. Freeman, A. Martinez, J. Mellerio, N. Sebire, V. Smith, K. Lindley, N. Shah.Great Ormond Street Hospital Department of Gastroenterology, London, UK

Aims: Epidermolysis bullosa (EB) is an inherited skin blistering condition. The aim of this study was to define the nature of gastrointestinal (GI) problems in children with EB.

Methods: All children in a supraregional paediatric EB centre were reviewed for GI problems.

Results: 224 cases were reviewed. 80 (31%) had epidermolysis bullosa simplex (EBS), 119 (53%) dystrophic type (RDEB), and 19 (8%) junctional type EB (JEB). GI problems were present in 139 (62%). Foregut problems of gastro-oesophageal reflux (GOR) affected 64/224 (28.6%), particularly common in RDEB (74%). Treatment was with high dose proton pump antagonists. Dysphagia from oesophageal strictures was only seen in the RDEB group 43/80 (53%) requiring treatment by repeated dilatations. Mid-gut problems were common in the JEB group with a quarter having a protein . . . [Full text of this article]