PERSPECTIVES
Newborn screening
Newborn screening for congenital toxoplasmosis: feasible, but benefits are not established
Centre for Epidemiology and Biostatistics, Institute of Child Health, London, UK
Correspondence to:
Correspondence to:
Dr R Gilbert
Centre for Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK; r.gilbert@ich.ucl.ac.uk
Perspective on the paper by Schmidt et al (see page661)
Keywords: toxoplasma gondii; congenital; neonatal screening; toxoplasmosis
| The first 150 words of the full text of this article appear below. |
The report on the Danish newborn screening programme for congenital toxoplasmosis in this month’s issue adds to evidence from similar programmes across the globe that newborn screening is feasible.1–5 Screening for toxoplasma specific IgM antibodies in newborn dried blood spots was first offered in 1988 by the New England Neonatal Screening Program. Since then, newborn screening programmes for congenital toxoplasmosis have been established in Denmark (in 1992),1 Poznan, Poland (in 1994),4 Porto Alegre, Brazil (in 1995),6 and Campos dos Goytazaces, Brazil (in 1999).7 In addition, screening studies have been conducted for a limited period in southern Sweden (1997–98)8 and Ireland (2005–07).9 The estimated birth prevalence of congenital toxoplasmosis per 10 000 live births reported by these programmes ranges from 0.7 in Sweden8 and 0.8 in Massachusetts,3 to 7.1 in Poland,4,10 and in Brazil, 5.4 in the private sector2 and 20 in the public sector.7 In European cohorts, approximately
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- The national neonatal screening programme for congenital toxoplasmosis in Denmark: results from the initial four years, 1999–2002
- D R Schmidt, B Hogh, O Andersen, J Fuchs, H Fledelius, and E Petersen
Arch. Dis. Child. 2006 91: 661-665.[Abstract] [Full Text] [PDF]
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Gomez-Marin, J E, delaTorre, A
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