- Encephalopathy
- Encephalitis
- Reye syndrome
- Febrile convulsion
- Myelitis
- Guillaine-Barré syndrome
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1 UCL Institute of Child Health, London, UK
2 Great Ormond Street Hospital for Children, London, UK
Correspondence to:
Correspondence to:
Prof. R Surtees
The Wolfson Centre, Mecklenburgh Square, London WC1N 2AP, UK; R.Surtees@ich.ucl.ac.uk
Keywords: encephalopathy; influenza
| The first 150 words of the full text of this article appear below. |
The neural complications of influenza are shown in box 1
. The commonest of these, particularly in young children from Japan and Taiwan, is influenza virus associated encephalopathy. Influenza virus associated encephalopathy is an acute non-inflammatory encephalopathy that presents with seizures and coma on the day, or the day after, influenza symptoms start.1 Influenza is characterised by the abrupt onset of a fever greater than 39°C, respiratory symptoms (rhinorrhoea, cough, and sore throat), myalgia (particularly of the back and limb muscles), and headache.2 In infants symptoms are often lethargy, poor feeding, apnoea, and interstitial pneumonia; older children may also have less specific symptoms of croup, otitis media, diarrhoea, and vomiting.
Influenza virus associated encephalopathy is a disease of young children with a peak incidence between 6 and 18 months of age.1 It has mostly been
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