PERSPECTIVES
Imaging
Is limited computed tomography the future for imaging the lungs of children with cystic fibrosis?
Correspondence to:
Correspondence to:
Dr S C Langton Hewer
Department of CF and Respiratory Medicine, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK; simon.langtonhewer@bris.ac.uk
Perspective on the paper by Jiménez et al (see page388)
Keywords: computed tomography; cystic fibrosis
| The first 150 words of the full text of this article appear below. |
In this issue of the Journal, Jiménez et al describe a new technique in high resolution computed tomography (HRCT) of the chest in children with cystic fibrosis (CF).1 HRCT is widely available to clinicians who care for children with CF; it has some advantages over plain chest radiography but exposes the child to more radiation. The HRCT technique described by Jiménez et al reduces the radiation exposure by limiting the number of slices to six. Will six slices be sufficient to provide the information that the clinician seeks?
Pulmonary disease in children with CF is characterised by impaired clearance of pathogens, resulting in intermittent and later permanent infection of the lower respiratory tract, with bacterial and fungal pathogens causing progressive mucous impaction and bronchiectasis. Asymptomatic infants with CF have been shown to have abnormalities in pulmonary function2,3 and to have airway inflammation on lavage studies.4,5 Plain chest radiographs traditionally
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